Incidence de l’HTA chez les agents SNCF en horaire atypique ou de jour

International audienc

Restauration de la Tourbière de Landemarais, vingt années de suivi

Procéder à la restauration de la dynamique naturelle d’un écosystème passe par un suivi scientifique efficace des opérations et de leurs effets écologiques. Après vingt ans de suivi de la réhabilitation de la tourbière de Landemarais en Bretagne, quels sont les résultats sur le maintien des espèces et des habitats ? Quelles sont les améliorations à envisager dans les pratiques de gestion

Restauration de la Tourbière de Landemarais, vingt années de suivi.

Procéder à la restauration de la dynamique naturelle d'un écosystème passe par un suivi scientifique efficace des opérations et de leurs effets écologiques. Après vingt ans de suivi de la réhabilitation de la tourbière de Landemarais en Bretagne, quels sont les résultats sur le maintien des espèces et des habitats ? Quelles sont les améliorations à envisager dans les pratiques de gestion

Impact de l’assec et de la remise en eau sur les compartiments biologiques (végétaux et cyanobactéries)

International audienc

Impact de l’assec et de la remise en eau sur les compartiments biologiques (végétaux et cyanobactéries)

International audienc

Evolution of anti-eCG antibodies in response to eCG doses and number of injections. Relation with rabbit does productivity

peer reviewedThe aim of this experiment was to study the kinetics of anti-eCG (equine chorionic gonadotrophin) antibodies in relation to eCG dose (8 or 25 IU) and number of injections (n = 11) in comparison with a control group (no injection), and to relate antibody production to sexual receptivity and productivity of rabbit does. In all, 124 lactating primiparous rabbit does were inseminated every 35 days for a year. Just before eCG injection (48 h before insemination), blood samples were collected from all the does to assay anti-eCG antibodies. The anti-eCG antibody binding rate, regardless of the injected dose, shows that none of the does developed detectable anti-eCG antibodies before the 7th injection. The level of detectable anti-eCG antibodies began to show an increase at the 7th injection and was significant only for the 25 IU dose at the 11th injection. At the end of the experiment, 15% and 39% of does treated with 8 and 25 IU, respectively, developed immunity to eCG (binding rate >6%: higher binding rate of the control group). Consequently, the immune response depends on the eCG dose and on the number of injections. Moreover, productivity of does estimated from the number of weaned rabbits produced per insemination is not influenced by the level of eCG antibodies (7.0 and 6.9 for binding rate <6% and binding rate 6%, respectively). Only 19 inseminations (n = 6 and n = 13 for 8 and 25 IU, respectively) were made on hyperimmune does. Consequently, the immune response to eCG seems to be marginal for rabbit does. Moreover, under the described experimental conditions, reproductive performances of hyperimmune does were not affecte

Focal brain ischemia in rat: acute changes in brain tissue T1 reflect acute increase in brain tissue water content.

International audienceSeveral recent studies have reported changes of brain tissue T(1) in ischemic models during the first minutes after occlusion of the middle cerebral artery (MCA). In order to assess whether these tissue T(1) changes are related to an increase in tissue water content, we performed T(1) (7 T) and tissue water content measurements in a rat model (n = 10, Sprague-Dawley) of focal cerebral ischemia (intraluminal occlusion model). The tissue water content was determined using a gravimetric technique. The animals were divided into two groups: an ischemic group, with an effective MCA occlusion (n = 6) and a control group, with animals having undergone sham surgery but no MCA occlusion (n = 4). In the ipsilateral cortex, the tissue water content was 81.1 +/- 0.7% at 2 h 15 min following ischemic insult (contralateral value: 79.3 +/- 0.5%). Concomitantly, the tissue T(1) in the ipsilateral cortex was 2062 +/- 60 ms at ischemia onset + 1 h (contralateral 1811 +/- 28 ms) and 2100 +/- 38 ms at ischemia onset + 2 h (contralateral 1807 +/- 18 ms). The tissue T(1) and tissue water content values measured in the contralateral area do not differ from the values obtained in the control group. A significant T(1) increase is observed at ischemia onset + 1 h (+ 14%) and ischemia onset (+ 2 h) + 16%, together with a significant increase in tissue water content (+ 2.3%). This suggests that there is an increase in tissue water content concomitant with cell swelling during the first hours of ischemia

Evolution of anti-eCG antibodies in response to eCG doses and number of injections. Relation with rabbit does productivity

peer reviewedThe aim of this experiment was to study the kinetics of anti-eCG (equine chorionic gonadotrophin) antibodies in relation to eCG dose (8 or 25 IU) and number of injections (n = 11) in comparison with a control group (no injection), and to relate antibody production to sexual receptivity and productivity of rabbit does. In all, 124 lactating primiparous rabbit does were inseminated every 35 days for a year. Just before eCG injection (48 h before insemination), blood samples were collected from all the does to assay anti-eCG antibodies. The anti-eCG antibody binding rate, regardless of the injected dose, shows that none of the does developed detectable anti-eCG antibodies before the 7th injection. The level of detectable anti-eCG antibodies began to show an increase at the 7th injection and was significant only for the 25 IU dose at the 11th injection. At the end of the experiment, 15% and 39% of does treated with 8 and 25 IU, respectively, developed immunity to eCG (binding rate >6%: higher binding rate of the control group). Consequently, the immune response depends on the eCG dose and on the number of injections. Moreover, productivity of does estimated from the number of weaned rabbits produced per insemination is not influenced by the level of eCG antibodies (7.0 and 6.9 for binding rate <6% and binding rate 6%, respectively). Only 19 inseminations (n = 6 and n = 13 for 8 and 25 IU, respectively) were made on hyperimmune does. Consequently, the immune response to eCG seems to be marginal for rabbit does. Moreover, under the described experimental conditions, reproductive performances of hyperimmune does were not affecte

Tumor arising in the periventricular region.

International audienc

Dynamic Echo-Planar MR Imaging of the Diaphragm for a 3D Dynamic Analysis

International audienceObjective: To prove the feasibility of 3D reconstructions of the diaphragm during respiratory cycle, using EPI sequences. Materials and Methods: EPI acquisition, 270 ms/image, on a healthy subject breathing spontaneously and at 0.1Hz. Continuously recorded respiratory signal allowed for retrospective synchronization with respiratory phases for reconstruction of successive diaphragm surfaces using a specifically designed software. Displacements, area and volume changes of the diaphragm were quantified. Results: Our measurements were comparable with literature data. Reconstructed surfaces allowed in vivo diaphragm dynamics evaluation, in terms of displacements, area and volume variations. Conclusion: EPI has adequate spatial and temporal resolution for studying diaphragm dynamics during natural breathing